Qingdao Oriental Tongxiang(China)/Life Bridge International(USA)
CAS NO.: 13422-55-4
Standard: JP XIV BP USP
Export Markets: Global
Methylcobalamin is a cobalamin used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary for amyotrophic lateral sclerosis. It is a form of vitamin B12 and differs from cyanocobalamin in that the cyanide is replaced by a methyl group.
Methylcobalamin has been studied in conjunction with sleep-wake rhythm disorders, where it appears to yield benefits, but at a low or inconsistent level.
Supplementation with megadoses of methylcobalamin has been advocated to protect the cognitive function of patients suffering methylcobalamin may help to remove brain-damaging level of the neurotransmitter glutamate. Methylcobalamin has been reported to have been used to reduce neurotoxicity and lower excess glutamate levels, resulting in the reduction of fatigue, stabilisation of mood, improvement if memory, and executive function. However, clinical trials using methylcobalamin have been small and, for the most part, have not been replicated or confirmed.
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