Contract Research

Contract Research from Buffalo BioLabs LLC

By: Buffalo BioLabs LLC  07/08/2014
Keywords: Oncology, Immunology, Drug Development

Buffalo BioLabs specializes in preclinical animal studies, analytical studies, as well as in identification/validation of novel pharmacological targets and discovery and preclinical development of drugs that effectively interact with these targets. Our extensive experience has been primarily concentrated in the fields of cancer, age-related diseases, radiation pathologies, immunological disorders and infectious diseases, yet it is fully applicable to other fields or types of diseases. The expertise of our research team, which is both broad and deep, has led to successful execution of numerous IND-enabling mechanistic and efficacy studies in a variety of in vitro and in vivo models. We offer a comprehensive range of research services focused on driving drug development from the earliest stages of discovery through advanced preclinical development. These services include development and validation of experimental models and assays and full characterization of novel drugs, spanning both conventional (e.g., efficacy, pharmacology, PK/PD, toxicity, metabolism) and аdvanced (e.g., systemic effects/side effects, molecular mechanisms, biomarker discovery and validation, target identification) aspects of drug development. BBL’s success in these types of studies stems from the team’s access to and experience with a rich, customizable research tool set, including: · cell-based readout and screening systems; · immunological and other bioanalytical assays; · clinically relevant animal models of diseases and therapies. BBL is comprised of four Research Services laboratories (Preclinical, Validation, Cell Biology and Immunology) and three Core Services groups (Chemistry and Bioanalytics, Histology and Animal Studies). Typically, a research project contracted to BBL involves contributions of experts from 2-3 of BBL’s Research Services teams as well as Core Services. Additional expertise and resources (e.g., tissue microarray analysis, high-throughput screening, genomics, access to a collection of primary tumors, etc.) are engaged through subcontracts to established academic partners (such as Roswell Park Cancer Institute).

Keywords: Analytical Chemistry, Analytical Laboratory, Analytical Services, Analytical Testing, Animal Models, Animal Studies, Animal Testing, Animal Toxicology, biomarkers testing, Biotechnology Research, Cell Biology, Chemical Analysis, compounds testing, Contract Research Organization, custom biology, discovery partnering, Drug Development, Drug Efficacy, Drug Research, Drug Studies, Efficacy Studies, Full-service Analytical Laboratory, Glp Studies, Histopathology, Immunohistochemistry, Immunology, IND-enabling studies, non-GLP studies, Oncology, Oncology CRO, Oncology Studies, pharmaceutical testing, Pharmacology, PK/PD, Preclinical Evaluation, preclinical experimentation, preclinical models, Preclinical Studies, Preclinical Testing, Research Models, Research Products And Services, Target Validation, Tissue Testing, translational experimentation,