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The primary active ingredient of ArterosilHP is rhamnan sulfate, derived from Monostroma nitidum, a rare green seaweed found in east Asia.Rhamnan sulfate, a negatively charged polysaccharide, was reported to posses anticoagulant and antithrombotic activity by some early studies13,14 and this was verified by other researchers later15.Rhamnan sulfate has a similar chemical structure to heparan sulfate found abundantly in human endothelial glycocalyx and may exert its biological activities by regenerating endothelial glycocalyx.
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